Breakthrough Anti-Integrin Therapy for Ocular Health

Risuteganib downregulates oxidative stress response and restores retinal homeostasis

Research suggests that risuteganib interferes with integrin functions that have been implicated in retinal diseases, giving it the potential for a broad-spectrum effect on different pathways of oxidative stress.

Risuteganib aims to regulate oxidative stress response upstream before it has a chance to initiate multiple pathways implicated in intermediate dry AMD and DME. Through these multiple channels, risuteganib helps reduce the cellular burden of oxidative stress in an effort to restore retinal homeostasis.1


a Animal retinopathy of prematurity [ROP] models
b Genomic analysis

1. Kaiser PK. Topline results from a prospective, double-masked, placebo-controlled phase-2b clinical study evaluating ALG-1001 (Luminate) in patients with diabetic macular edema. ARVO, May 2017.